Research for acupuncture has been traumatically increased during past 40 years.  Based on medical research database PubMed, a total of 232acupuncture research papers been published in 1980. Number of research paper regarding acupuncture haven been increased up to 2863 in 2020.  Those research works provide wild range scientific data to guide acupuncture treatment in clinic.  In here, we selected a few popular topics to help our patient to understand scientific bases of acupuncture treatment.